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A synthespian is any synthetic actor. A portmanteau of the words synthetic, meaning not of natural origin, and thespian, meaning dramatic actor. The dinosaurs in Jurassic Park, for instance, were animatronic synthespians created by Stan Winston Studios. Aki Ross from the movie Final Fantasy: The Spirits Within was an entirely computer-generated synthespian.
The term "synthespian" was created by Jeff Kleiser and Diana Walczak of Kleiser-Walczak Construction Company. When they were assembling a synthetic thespian for their project, "Nestor Sextone for President", they coined the term "synthespian".